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CHE 501: Organic Chemistry

The core graduate course in organic chemistry. The course aims to provide chemistry graduate students with a broad set of skills in physical organic chemistry and reaction mechanisms, which may be applied to research in all subdisciplines of chemistry. Common carbon-carbon bond forming reactions and functional group manipulations are used as the framework for discussions of acids and bases, the kinetic determination of reaction mechanisms, and the nature of interactions between and within molecules that are the underlying cause of substituent effects on reactions rate. Problem solving skills are developed in discussions of reaction kinetics, stereochemistry, conformational analysis, reactivity-selectivity relationships and other selected topics.